title_body: Can I make custom fonts show up in iBooks? Is it possible to include custom fonts in an ebook and have them show up in iBooks, or can you only use the various default fonts listed on the device?
upvoted_answer: It is certainly possible to embed custom fonts and have them be used in iBooks, as well as on other EPUB reading systems. The process is known as embedding. Embedded fonts are simply included in the .zip archive that comprises the EPUB file, and then referenced properly in all the relevant content files. Places you will need to reference them include:
  
  CSS file
  
  This is just like using fonts on the web: the first thing you need to do is define @font-face:
  
  @font-face {
    font-family: roboto;
    src: url('fonts/Roboto/Roboto-Regular.ttf')
  }
  
  
  and then use that declaration in for whichever styles you'd like to use that font:
  
  p.intro {
    font-family: roboto;
    font-weight: normal;
    font-style: normal;
  }
  
  
  content.opf file
  
  Just like all the other files in your EPUB, you'll need to include any font files you're embedding in the &lt;manifest&gt; of your .opf file:
  
  &lt;item id="Roboto-Regular_ttf" href="fonts/Roboto-Regular.ttf" media-type="application/x-font-truetype" /&gt;
  
  
  The above steps are sufficient for most reading systems, but iBooks has one more hoop to jump through:
  
  com.apple.ibooks.display-options.xml
  
  This is a file that goes in the META-INF folder of the EPUB, rather than the OEBPS folder, and as the name suggests it's iBooks-specific. Neither this file nor the container.xml file need to be declared in the &lt;manifest&gt;, so don't worry about that. Here is the file in its entirety:
  
  &lt;?xml version="1.0" encoding="UTF-8" standalone="yes"?&gt;
  &lt;display_options&gt;
  &lt;platform name="*"&gt;
  &lt;option name="specified-fonts"&gt;true&lt;/option&gt;
  &lt;/platform&gt;
  &lt;/display_options&gt;
  
  
  A more in-depth writeup can be found on Liz Castro's excellent blog. As noted elsewhere, be aware that there are some potential hurdles, both legal and practical, to embedding fonts.