text: Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children.
  Cerebral blood flow (CBF) was measured with continuous arterial spin-labeling perfusion magnetic resonance (MR) imaging in 14 children with sickle cell disease and seven control subjects. Mean CBF values were higher in patients (P <.005) than in control subjects in all cerebral artery territories. Three patients had decreased CBF in right anterior and middle cerebral artery territories compared with CBF on the left, and one patient had a profound decrease in CBF in all three territories in the right hemisphere. Baseline CBF was significantly decreased in territories seen as unaffected on conventional MR images and MR angiograms in four children with sickle cell disease.
  
entities: ['Sickle cell']
entities: Cell
entities: PMID-12663827_T1
entities: ['arterial']
entities: Multi-tissue_structure
entities: PMID-12663827_T2
entities: ['Cerebral']
entities: Organ
entities: PMID-12663827_T3
entities: ['blood']
entities: Organism_substance
entities: PMID-12663827_T4
entities: ['arterial']
entities: Multi-tissue_structure
entities: PMID-12663827_T5
entities: ['sickle cell']
entities: Cell
entities: PMID-12663827_T6
entities: ['cerebral artery']
entities: Multi-tissue_structure
entities: PMID-12663827_T7
entities: ['right anterior']
entities: Multi-tissue_structure
entities: PMID-12663827_T8
entities: ['cerebral artery']
entities: Multi-tissue_structure
entities: PMID-12663827_T9
entities: ['right hemisphere']
entities: Organism_subdivision
entities: PMID-12663827_T10
entities: ['sickle cell']
entities: Cell
entities: PMID-12663827_T11